Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1155810

C=C(CCN(C)C)C(=O)O.Cl

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EGFR known ✓ P00533 2/20 0.37
KDM4A O75164 11/20 0.37
KDM4C Q9H3R0 11/20 0.37
TET2 Q6N021 4/20 0.35
UBE2N P61088 1/20 0.35
GSR P00390 1/20 0.34
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
KDM5A P29375 1/20 0.33
KDM7A Q6ZMT4 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28345645 0.98 KDM4A (0.36) KDM4AKDM4CEGFRTET2UBE2N
SCHEMBL30785151 0.98 TET2 (0.37) KDM4AKDM4CEGFRTET2TET3
SCHEMBL22345 0.98 TET2 (0.37) KDM4AKDM4CEGFRTET2TET3
Ammonia Solution, Strong SCHEMBL9070321 0.95 TET2 (0.35) KDM4AKDM4CEGFRTET2TET3
Acetic Acid SCHEMBL11512957 0.93 TET2 (0.34) KDM4AKDM4CEGFRTET2TET3
Chloromethane SCHEMBL124968 0.93 TET2 (0.39) KDM4AKDM4CEGFRTET2TET3
Bromomethane SCHEMBL7095815 0.93 TET2 (0.34) KDM4AKDM4CEGFRTET2TET3
Sulfuric Acid SCHEMBL28351007 0.92 GSR (0.38) KDM4AKDM4CEGFRTET2UBE2N
SCHEMBL8736374 0.89 MAPT (0.39) KDM4AKDM4CEGFRTET2TET3
SCHEMBL4242756 0.89 KDM4A (0.38) KDM4AKDM4CKDM5AKDM7APHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115516030-A Compositions and methods for increasing wet and dry strength 凯米拉公司 2022-12-23 CN claimed
CN-115516031-A GPAM compositions and methods 凯米拉公司 2022-12-23 CN claimed
CN-109153948-B Acidic cleaning, disinfecting and germicidal compositions with reduced fogging through the use of high molecular weight water-in-oil emulsion polymers 埃科莱布美国股份有限公司 2021-03-16 CN claimed
US-10655080-B2 Corn syrup, an inversion aid for water-in-oil polymer emulsions ECOLAB USA INC. (US) 2020-05-19 US claimed
WO-2017143136-A1 CORN SYRUP, AN INVERSION AID FOR WATER-IN-OIL POLYMER EMULSIONS ECOLAB USA INC. (US) 2017-08-24 WO claimed
US-20170233674-A1 CORN SYRUP, AN INVERSION AID FOR WATER-IN-OIL POLYMER EMULSIONS APERGY ESP SYSTEMS, LLC 2017-08-17 US claimed
US-12037544-B2 Crosslinking of swellable polymer with PEI CONOCOPHILLIPS COMPANY (US) 2024-07-16 US disclosed
EP-4373825-A1 NITRILE SUMO INHIBITORS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2024-05-29 EP disclosed
EP-4169999-A1 CROSSLINKING OF SWELLABLE POLYMER WITH PEI ConocoPhillips Company (US) 2023-04-26 EP disclosed
CN-115726215-A Composition and method for making paper 埃科莱布美国股份有限公司 2023-03-03 CN disclosed
WO-2023004376-A1 NITRILE SUMO INHIBITORS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2023-01-26 WO disclosed
CN-115516030-A Compositions and methods for increasing wet and dry strength 凯米拉公司 2022-12-23 CN disclosed
CN-115516031-A GPAM compositions and methods 凯米拉公司 2022-12-23 CN disclosed
EP-0201186-B1 METHOD OF TREATING PHOTOGRAPHIC WASTE SOLUTIONS AND AUTOMATIC PHOTOGRAPH PROCESSOR KONICA CORPORATION (JP) 1990-05-30 EP disclosed
EP-0290753-A1 Process for preparing polymer beads from water-soluble ethylenically unsatarated monomers BASF Aktiengesellschaft (DE) 1988-11-17 EP disclosed
EP-0243768-A2 Process for preparing polymers in pearl form based on hydrosoluble ethylenically unsaturated monomers BASF Aktiengesellschaft (DE) 1987-11-04 EP disclosed
EP-0201186-A1 Method of treating photographic waste solutions and automatic photograph processor KONICA CORPORATION (JP) 1986-11-12 EP disclosed
EP-0113038-B1 PROCESS FOR PREPARING CONCENTRATED AQUEOUS SOLUTIONS OF QUATERNIZED PRODUCTS FROM TERTIARY AMINO ALKYL ESTERS OR AMIDES OF ACRYLIC OR METHACRYLIC ACIDS BASF Aktiengesellschaft (DE) 1986-09-10 EP disclosed
EP-0192183-A2 Weakly cross-linked polymers or copolymers in the form of particles and quickly swellable in water, method for making them and their use in hygienic articles RÖHM GMBH (DE) 1986-08-27 EP disclosed
EP-0113038-A2 Process for preparing concentrated aqueous solutions of quaternized products from tertiary amino alkyl esters or amides of acrylic or methacrylic acids BASF Aktiengesellschaft (DE) 1984-07-11 EP disclosed