Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148513 | 1.00 | NFKB1 (0.48) | NFKB1BLMPMP22KMT2AC5AR1 | |
| SCHEMBL7916416 | 0.92 | NFKB1 (0.57) | NFKB1BLMPMP22KMT2APOLB | |
| SCHEMBL30352666 | 0.92 | NFKB1 (0.57) | NFKB1BLMPMP22KMT2APOLB | |
| SCHEMBL22714045 | 0.89 | PDE4A (0.43) | NFKB1BLMPMP22ADRB3 | |
| SCHEMBL17024332 | 0.87 | FFAR4 (0.51) | NFKB1BLMPMP22MAPTTDP1 | |
| SCHEMBL4165459 | 0.87 | MRGPRX4 (0.52) | NFKB1BLMPMP22KMT2ATAAR1 | |
| SCHEMBL4659219 | 0.87 | MRGPRX4 (0.52) | NFKB1BLMPMP22KMT2ATAAR1 | |
| SCHEMBL4866879 | 0.86 | ELANE (0.47) | NFKB1C5AR1F2ADRB2ADRB1 | |
| SCHEMBL7153073 | 0.86 | ELANE (0.47) | NFKB1C5AR1F2ADRB2ADRB1 | |
| SCHEMBL4376651 | 0.85 | POLB (0.43) | NFKB1KMT2AC5AR1POLBUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58134060-A | — | — | None | — | — | JP | disclosed |
| US-5514694-A | ENZYME INHIBITORS | GEORGIA TECH RESEARCH CORP (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0650368-A1 | USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF MEDICAL CONDITIONS ASSOCIATED WITH INCREASED CALPAIN ACTIVITY | CORTEX PHARMACEUTICALS, INC. (US) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994000095-A2 | USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF MEDICAL CONDITIONS ASSOCIATED WITH INCREASED CALPAIN ACTIVITY | CORTEX PHARMACEUTICALS, INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| JP-S58134060-A | PRODUCTION OF ALPHA-AMINOMETHYLBENZYL ALCOHOL DERIVATIVE | OTA SEIYAKU KK | 1983-08-10 | — | — | JP | disclosed |