Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | F7 | P08709 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30352666 | 1.00 | NFKB1 (0.57) | NFKB1BLMPMP22SMPD1HDAC1 | |
| SCHEMBL9070525 | 0.92 | NFKB1 (0.48) | NFKB1BLMPMP22F2F10 | |
| SCHEMBL7148513 | 0.92 | NFKB1 (0.48) | NFKB1BLMPMP22F2F10 | |
| SCHEMBL8843624 | 0.89 | SMPD1 (0.53) | SMPD1HDAC1HDAC8HDAC6F2 | |
| SCHEMBL7919807 | 0.89 | NFKB1 (0.51) | NFKB1BLMPMP22SMPD1HDAC1 | |
| SCHEMBL7919811 | 0.87 | NFKB1 (0.55) | NFKB1BLMPMP22 | |
| SCHEMBL9586284 | 0.86 | SMPD1 (0.56) | SMPD1HDAC1HDAC8HDAC6F2 | |
| SCHEMBL2060104 | 0.86 | SMPD1 (0.56) | SMPD1HDAC1HDAC8HDAC6F2 | |
| SCHEMBL24162320 | 0.85 | SMPD1 (0.49) | BLMSMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL17024332 | 0.85 | FFAR4 (0.51) | NFKB1BLMPMP22MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3777979-B1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) | 2024-01-17 | — | — | EP | disclosed |
| EP-3777979-B1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) | 2024-01-17 | — | — | EP | disclosed |
| CN-110407741-B | Anti-inflammatory compound and preparation and application thereof | 启元生物(杭州)有限公司 | 2023-03-21 | — | — | CN | disclosed |
| US-11440886-B2 | Anti-inflammatory compound, and preparation and use thereof | E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd. (CN) | 2022-09-13 | — | — | US | disclosed |
| EP-3777979-A1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | Vivavision Biotech, Inc. (CN) | 2021-02-17 | — | — | EP | disclosed |
| EP-3777979-A1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | Vivavision Biotech, Inc. (CN) | 2021-02-17 | — | — | EP | disclosed |
| US-20200377460-A1 | ANTI-INFLAMMATORY COMPOUND, AND PREPARATION AND USE THEREOF | VIVAVISION BIOTECH, INC. (CN) | 2020-12-03 | — | — | US | disclosed |
| US-20200377460-A1 | ANTI-INFLAMMATORY COMPOUND, AND PREPARATION AND USE THEREOF | VIVAVISION BIOTECH, INC. (CN) | 2020-12-03 | — | — | US | disclosed |
| CN-110407741-A | A kind of anti-inflammatory compound and its preparation and application | JIAXING WEIMOU BIO TECH CO LTD | 2019-11-05 | — | — | CN | disclosed |
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-4186129-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, ANTICONVULSANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11440886-B2 | Anti-inflammatory compound, and preparation and use thereof | PDE4B, PDE4A, PDE7A | NFKB1 116/4885BLM 3236/4885PMP22 1696/4885 |
| US-20200377460-A1 | ANTI-INFLAMMATORY COMPOUND, AND PREPARATION AND USE THEREOF | PDE4B, PDE4A, PDE7A | NFKB1 116/4885BLM 3236/4885PMP22 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.