Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843209 | 0.80 | DYRK1A (0.45) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5506754 | 0.80 | DYRK1A (0.45) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3411791 | 0.80 | CYP1A1 (0.45) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28196403 | 0.78 | SLC6A4 (0.41) | CLK4DYRK1ACYP2D6ALDH1A1HSD17B2 | |
| SCHEMBL2377417 | 0.78 | HDAC4 (0.55) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9430884 | 0.78 | DYRK1A (0.44) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9716169 | 0.78 | TAAR1 (0.41) | HSD17B2GAAHSD17B1 | |
| SCHEMBL12472636 | 0.72 | NPC1 (0.51) | ALDH1A1LMNAHDAC4HDAC8MAOB | |
| SCHEMBL1274110 | 0.72 | DYRK1A (0.40) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18585090 | 0.72 | KDM4E (0.31) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507854-B1 | METHODS FOR DIAGNOSING HUMAN INFLUENZA AND 4-POSITION MODIFIED CHROMOGENIC N-ACETYLNEURAMINIC ACID SUBSTRATES FOR USE THEREIN | SYMEX CORP (US) | 1996-11-27 | — | — | EP | claimed |
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |