Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | STK4 | Q13043 | 1/20 | 0.35 |
| ▸ | STK3 | Q13188 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070549 | 0.78 | CLK4 (0.41) | GAAHSD17B1HSD17B2 | |
| SCHEMBL7873510 | 0.78 | ESR2 (0.46) | TAAR1ALOX5ESR2GAAKMT2A | |
| SCHEMBL9648703 | 0.78 | ALOX5 (0.44) | TAAR1ALOX5ESR2CHRNB4CHRNA3 | |
| SCHEMBL16719910 | 0.75 | ALOX5 (0.55) | TAAR1ALOX5ESR2 | |
| SCHEMBL18585090 | 0.75 | KDM4E (0.31) | GAA | |
| SCHEMBL16058080 | 0.75 | ALOX5 (0.42) | TAAR1ALOX5ESR2CHRNB4CHRNA3 | |
| SCHEMBL7006949 | 0.75 | ALOX5 (0.42) | TAAR1ALOX5ESR2IDO1 | |
| SCHEMBL5321256 | 0.74 | DHPS (0.44) | ALOX5KMT2AHTR7 | |
| SCHEMBL18415193 | 0.73 | STK4 (0.47) | TAAR1ALOX5SLC9A1ESR2KCNQ2 | |
| SCHEMBL7464317 | 0.70 | NPC1 (0.41) | TAAR1ALOX5GAAKMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4208255-A | — | — | None | — | — | JP | disclosed |
| JP-H04208255-A | ALKYLAMINO-AND ALKYLAMINO ALKYL DIARYLKETONE AND ITS PREPARATION | HOECHST ROUSSEL PHARMACEUT INC | 1992-07-29 | — | — | JP | disclosed |