⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544939 | 0.81 | LMNA (0.39) | — | |
| SCHEMBL16108550 | 0.81 | — | — | |
| SCHEMBL30558884 | 0.79 | LMNA (0.37) | — | |
| SCHEMBL4811228 | 0.79 | OPRM1 (0.39) | — | |
| SCHEMBL8901960 | 0.79 | LMNA (0.37) | — | |
| SCHEMBL30558883 | 0.79 | LMNA (0.37) | — | |
| SCHEMBL3209475 | 0.79 | SLC1A2 (0.36) | — | |
| SCHEMBL9860798 | 0.79 | HTR2C (0.32) | — | |
| SCHEMBL6905081 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL167171 | 0.78 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107278215-B | High pressure polymerization process for preparing polyethylene | SABIC环球技术有限责任公司 | 2020-04-14 | — | — | CN | disclosed |
| EP-0446725-B1 | Base resistant fluoroelastomers with improved processibility and curability | DU PONT (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5102965-A | Radical catalyzed emulsion polymerization in presence of iodine compound; telomerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0446725-A1 | Base resistant fluoroelastomers with improved processibility and curability | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |
| US-5037921-A | Base resistant fluoroelastomers with improved processibility and curability | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-08-06 | — | — | US | disclosed |