Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070589 | 0.92 | CA12 (0.43) | KDM4EALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL8307015 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL27445438 | 0.85 | SMN1; SMN2 (0.46) | KDM4EALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL8306870 | 0.83 | ALDH1A1 (0.39) | KDM4EALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL8554644 | 0.82 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL16541035 | 0.82 | MAPT (0.48) | KDM4EALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL8307013 | 0.82 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL8326230 | 0.79 | CYP19A1 (0.44) | KDM4EALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL679245 | 0.79 | ALDH1A1 (0.46) | KDM4EALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL27445439 | 0.78 | SMN1; SMN2 (0.43) | KDM4EALDH1A1NPSR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7330751-A | — | — | None | — | — | JP | disclosed |
| JP-8003154-A | — | — | None | — | — | JP | disclosed |
| JP-H083154-A | OXALYLAMINO-BENZOFURAN AND BENZOTHIENYL DERIVATIVE | BAYER AG | 1996-01-09 | — | — | JP | disclosed |
| JP-H07330751-A | AMINO-BENZOFURYL-AND THIENYL-DERIVATIVE | BAYER AG | 1995-12-19 | — | — | JP | disclosed |