Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12642017 | 0.89 | ALDH1A1 (0.50) | PKMALDH1A1MAPTLMNACYP1A2 | |
| SCHEMBL4505612 | 0.86 | FLT1 (0.54) | PKMALDH1A1MAPTHPGDLMNA | |
| SCHEMBL4528141 | 0.85 | KMT2A (0.65) | PKMALDH1A1MAPTLMNACYP1A2 | |
| SCHEMBL907263 | 0.83 | CA12 (0.55) | ALDH1A1MAPTLMNASMN1; SMN2HSD11B1 | |
| SCHEMBL21151897 | 0.83 | ALDH1A1 (0.45) | PKMALDH1A1MAPTHPGDLMNA | |
| SCHEMBL17688654 | 0.83 | ALDH1A1 (0.48) | PKMALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL13333146 | 0.83 | MAPT (0.50) | PKMALDH1A1MAPTHPGDLMNA | |
| SCHEMBL23280908 | 0.82 | ALDH1A1 (0.44) | PKMALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL17402095 | 0.82 | KMT2A (0.46) | PKMALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL21151875 | 0.82 | ALDH1A1 (0.47) | PKMALDH1A1MAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133099-B1 | Conjugated biological molecules and their preparation | POLYTHERICS LTD (GB) | 2017-04-19 | — | — | EP | disclosed |
| US-9439974-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2016-09-13 | — | — | US | disclosed |
| EP-2253330-B1 | Conjugated biological molecules and their preparation | POLYTHERICS LTD (GB) | 2015-08-19 | — | — | EP | disclosed |
| EP-2277550-B1 | Process for the preparation of conjugated biological molecules. | POLYTHERICS LTD (GB) | 2015-04-29 | — | — | EP | disclosed |
| US-20140369960-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | ABZENA (CAMBRIDGE) LIMITED (GB) | 2014-12-18 | — | — | US | disclosed |
| US-8816051-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2014-08-26 | — | — | US | disclosed |
| US-20110182855-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | POLYTHERICS LIMITED (GB) | 2011-07-28 | — | — | US | disclosed |
| US-7939630-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2011-05-10 | — | — | US | disclosed |
| EP-2277550-A1 | Conjugated biological molecules and their preparation | Polytherics Limited (GB) | 2011-01-26 | — | — | EP | disclosed |
| EP-2253330-A2 | Conjugated biological molecules and their preparation | Polytherics Limited (GB) | 2010-11-24 | — | — | EP | disclosed |
| EP-1893741-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | Beckman Coulter, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007001817-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | BECKMAN COULTER, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060292559-A1 | Cell-based microarrays, and methods for their preparation and use | BECKMAN COULTER, INC. (US) | 2006-12-28 | — | — | US | disclosed |
| US-20060210526-A1 | polyoxyethylene glycol-protein conjugate linked via linking group | ABZENA (CAMBRIDGE) LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |
| EP-1648518-A2 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | Polytherics Limited (GB) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005007197-A2 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | POLYTHERICS LIMITED (GB) | 2005-01-27 | — | — | WO | disclosed |
| US-5648213-A | IMMUNOASSAY | BECKMAN INSTRUMENTS, INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0779934-A1 | COMPOSITIONS AND METHODS FOR USE IN DETECTION OF ANALYTES | BECKMAN INSTRUMENTS, INC. (US) | 1997-06-25 | — | — | EP | disclosed |
| WO-1996006948-A1 | COMPOSITIONS AND METHODS FOR USE IN DETECTION OF ANALYTES | BECKMAN INSTRUMENTS, INC. (US) | 1996-03-07 | — | — | WO | disclosed |
| EP-0562624-A2 | Stabilization of functional proteins | Modrovich, Ivan E. (US) | 1993-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140369960-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | F13B, F13A1, ZYX | PKM 2366/4885ALDH1A1 3197/4885MAPT 4472/4885 |
| US-20110182855-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | F13B, ZYX, F13A1 | PKM 2623/4885ALDH1A1 3013/4885MAPT 4643/4885 |
| US-20060210526-A1 | polyoxyethylene glycol-protein conjugate linked via linking group | F13A1, F13B, SSB | PKM 3131/4885ALDH1A1 4140/4885MAPT 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.