SCHEMBL12642017

SCHEMBL12642017

Cc1ccc(C(=O)C(CS(=O)(=O)c2ccc(C)cc2)CS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
MAPT P10636 3/20 0.49
RECQL P46063 1/20 0.49
HSD11B1 P28845 1/20 0.49
KMT2A Q03164 4/20 0.48
PAX8 Q06710 1/20 0.48
LMNA P02545 1/20 0.48
ADAM17 P78536 1/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
PKM P14618 2/20 0.47
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17688654 0.94 ALDH1A1 (0.48) ALDH1A1MAPTRECQLHSD11B1KMT2A
SCHEMBL907263 0.94 CA12 (0.55) ALDH1A1MAPTRECQLHSD11B1KMT2A
SCHEMBL21151897 0.94 ALDH1A1 (0.45) ALDH1A1MAPTRECQLHSD11B1KMT2A
SCHEMBL13333146 0.94 MAPT (0.50) ALDH1A1MAPTRECQLHSD11B1KMT2A
SCHEMBL23280908 0.92 ALDH1A1 (0.44) ALDH1A1MAPTRECQLHSD11B1KMT2A
SCHEMBL907548 0.92 ALDH1A1 (0.51) ALDH1A1MAPTRECQLHSD11B1KMT2A
SCHEMBL907404 0.92 ALDH1A1 (0.47) ALDH1A1MAPTRECQLHSD11B1KMT2A
SCHEMBL21151875 0.92 ALDH1A1 (0.47) ALDH1A1MAPTRECQLHSD11B1KMT2A
SCHEMBL17402095 0.92 KMT2A (0.46) ALDH1A1MAPTRECQLHSD11B1KMT2A
SCHEMBL17664887 0.91 BCHE (0.46) ALDH1A1MAPTRECQLHSD11B1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4282434-A2 ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF Abzena (UK) Limited (GB) 2023-11-29 EP disclosed
US-20230114866-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES SYNAFFIX B.V. (NL) 2023-04-13 US disclosed
WO-2011077067-A1 POLYMER CONJUGATES OF NON-GLYCOSYLATED ERYTHROPOIETIN POLYTHERICS LIMITED (GB) 2011-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230114866-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES FUT5, FUCA1, FUT6 ALDH1A1 928/4885MAPT 2954/4885RECQL 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.