Sugi Predict

Sugi Predict / Compounds / SCHEMBL9070728

SCHEMBL9070728

SCHEMBL9070728

C=C1[C@H](CC(C)(C)[Si](C)(C)O)C/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@@H](C)CCCC(C)(C)C)CC[C@@H]23)C[C@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ VDR P11473 11/20 0.54
▸ CYP24A1 Q07973 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9070736 0.93 VDR (0.52) VDRCYP24A1
SCHEMBL14389713 0.93 VDR (0.50) VDRCYP24A1
SCHEMBL9010530 0.92 VDR (0.60) VDRCYP24A1
SCHEMBL13090106 0.91 VDR (0.49) VDR
SCHEMBL14146430 0.91 VDR (0.49) VDR
SCHEMBL19158370 0.91 VDR (0.49) VDR
SCHEMBL18059319 0.91 VDR (0.49) VDR
SCHEMBL14755286 0.91 VDR (0.48) VDR
SCHEMBL14731531 0.91 VDR (0.48) VDR
SCHEMBL14389716 0.90 VDR (0.48) VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8188064-B2 Reducing cell differentiation of adipocyte; reducing body fat WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-05-29 — — US disclosed