SCHEMBL9010530

C=C1[C@H](O[Si](C)(C)C(C)(C)C)CC(=C/C=C2\CCC[C@]3(C)[C@@H]([C@@H](C)CCCC(C)(C)C)CC[C@@H]23)C[C@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.64

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	VDR	P11473	10/20	0.60

▸	CYP24A1	Q07973	1/20	0.56

▸	SREBF1	P36956	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14357531	0.93	VDR (0.56)	VDRCYP24A1
SCHEMBL9010622	0.93	VDR (0.56)	VDRCYP24A1
SCHEMBL14489134	0.92	VDR (0.57)	VDRCYP24A1SREBF1
SCHEMBL9070728	0.92	VDR (0.54)	VDRCYP24A1
SCHEMBL13790494	0.92	VDR (0.56)	VDRCYP24A1
SCHEMBL3865811	0.92	VDR (0.56)	VDRCYP24A1
SCHEMBL9010583	0.91	VDR (0.57)	VDRCYP24A1
SCHEMBL12634985	0.90	VDR (0.54)	VDRCYP24A1
SCHEMBL14409184	0.90	VDR (0.54)	VDRCYP24A1
SCHEMBL13641657	0.90	VDR (0.54)	VDRCYP24A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8188064-B2	Reducing cell differentiation of adipocyte; reducing body fat	WISCONSIN ALUMNI RESEARCH FOUNDATION (US)	2012-05-29	—	—	US	disclosed