Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 5/20 | 0.42 |
| ▸ | NOS1 | P29475 | 5/20 | 0.42 |
| ▸ | NOS2 | P35228 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28766988 | 1.00 | — | — | |
| SCHEMBL14548854 | 1.00 | NOS3 (0.42) | NOS3NOS1NOS2KMT2AMEN1 | |
| SCHEMBL12422789 | 1.00 | NOS3 (0.42) | NOS3NOS1NOS2KMT2AMEN1 | |
| SCHEMBL368667 | 0.90 | — | — | |
| SCHEMBL16925311 | 0.75 | NOS1 (0.42) | NOS3NOS1NOS2KMT2AMEN1 | |
| SCHEMBL18531661 | 0.75 | NOS1 (0.42) | NOS3NOS1NOS2KMT2AMEN1 | |
| SCHEMBL23435265 | 0.71 | NOS3 (0.39) | NOS3NOS1NOS2KMT2AMEN1 | |
| SCHEMBL22102659 | 0.71 | NOS3 (0.39) | NOS3NOS1NOS2KMT2AMEN1 | |
| SCHEMBL18306439 | 0.71 | NOS3 (0.39) | NOS3NOS1NOS2KMT2AMEN1 | |
| SCHEMBL23333999 | 0.71 | NOS3 (0.39) | NOS3NOS1NOS2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128481-A1 | NITROGENATED 5-MEMBERED HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-22 | — | — | WO | disclosed |