Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.38 |
| ▸ | GIPR | P48546 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GCG | P01275 | 1/20 | 0.32 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.31 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.31 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.31 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.31 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.31 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.31 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.31 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.31 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070789 | 0.84 | GCGR (0.40) | GCGRGIPRKCNH2ADCY6ADCY3 | |
| SCHEMBL721555 | 0.80 | GCGR (0.55) | GCGRGIPRKCNH2GCG | |
| SCHEMBL719157 | 0.76 | GCGR (0.51) | GCGRGIPRKCNH2 | |
| SCHEMBL717614 | 0.75 | CCKBR (0.38) | GCGRGIPRKCNH2GCGADCY6 | |
| SCHEMBL3397752 | 0.73 | CCKBR (0.39) | GCGRGIPRKCNH2GCGOXER1 | |
| SCHEMBL719164 | 0.69 | GCGR (0.55) | GCGRGIPRKCNH2OXER1 | |
| SCHEMBL716441 | 0.69 | GCGR (0.53) | GCGRGIPRKCNH2 | |
| SCHEMBL718652 | 0.68 | OXER1 (0.48) | OXER1 | |
| SCHEMBL27852299 | 0.66 | ITGB3 (0.47) | GCGRGIPRKCNH2GCGADCY6 | |
| SCHEMBL717989 | 0.59 | KMT2A (0.43) | GCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |