SCHEMBL9070825 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	GCK	P35557	14/20	0.56

▸	RARA	P10276	1/20	0.45

▸	RARB	P10826	1/20	0.45

▸	HCAR3	P49019	3/20	0.43

▸	NPC1	O15118	1/20	0.42

▸	RAB9A	P51151	1/20	0.42

▸	SMN1; SMN2	Q16637	1/20	0.42

▸	PDE4A	P27815	1/20	0.41

▸	PDE4B	Q07343	1/20	0.41

▸	PDE4C	Q08493	1/20	0.41

▸	PDE4D	Q08499	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9070871	0.90	GCK (0.66)	GCKRARARARBHCAR3
SCHEMBL9070873	0.85	GCK (0.64)	GCKRARARARB
SCHEMBL2667714	0.82	GCK (0.76)	GCKRARARARB
SCHEMBL2667604	0.81	GCK (0.57)	GCKRARARARBHCAR3
SCHEMBL2667932	0.80	GCK (0.51)	GCKRARARARBHCAR3
SCHEMBL9070821	0.77	GCK (0.55)	GCKRARARARBHCAR3
SCHEMBL9070823	0.77	GCK (0.54)	GCKRARARARBHCAR3
SCHEMBL2667954	0.77	GCK (0.76)	GCKRARARARB
SCHEMBL9070896	0.76	HCAR3 (0.52)	GCKRARARARBHCAR3
SCHEMBL9070824	0.76	SMN1; SMN2 (0.44)	NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009083553-A1	AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS	RHEOSCIENCE A/S (DK)	2009-07-09	—	—	WO	disclosed