Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.55 |
| ▸ | RARA | P10276 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 2/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070871 | 0.87 | GCK (0.66) | GCKRARARARBHCAR3RARG | |
| SCHEMBL2667743 | 0.85 | GCK (0.63) | GCKRARARARBRARG | |
| SCHEMBL9070823 | 0.81 | GCK (0.54) | GCKRARARARBHCAR3RARG | |
| SCHEMBL9070822 | 0.80 | RAB9A (0.47) | — | |
| SCHEMBL2667936 | 0.79 | GCK (0.51) | GCKRARARARBHCAR3RARG | |
| SCHEMBL9070885 | 0.78 | ALDH1A1 (0.47) | — | |
| SCHEMBL9070887 | 0.78 | RAB9A (0.51) | GCK | |
| SCHEMBL2667604 | 0.78 | GCK (0.57) | GCKRARARARBHCAR3 | |
| SCHEMBL2667497 | 0.78 | SCD (0.52) | — | |
| SCHEMBL9070825 | 0.77 | GCK (0.56) | GCKRARARARBHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |