Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667996 | 0.94 | L3MBTL1 (0.54) | GCKRARARARBRARGALDH1A1 | |
| SCHEMBL2667363 | 0.94 | GCK (0.54) | GCKRARARARBRARGL3MBTL1 | |
| SCHEMBL9070837 | 0.88 | GCK (0.43) | GCKALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9070929 | 0.87 | GCK (0.55) | GCKRARARARBRARG | |
| SCHEMBL2667440 | 0.85 | GCK (0.66) | GCKRARARARBRARG | |
| SCHEMBL2667519 | 0.85 | PTGDR (0.56) | GCKALDH1A1SMN1; SMN2 | |
| SCHEMBL2667688 | 0.84 | GCK (0.63) | GCKRARARARBRARG | |
| SCHEMBL9071043 | 0.84 | GCK (0.58) | GCKRARARARBRARG | |
| SCHEMBL9070933 | 0.83 | GCK (0.58) | GCKRARARARBRARG | |
| SCHEMBL9071017 | 0.83 | GCK (0.52) | GCKRARGALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |