Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667993 | 0.94 | L3MBTL1 (0.47) | GCKKCNH2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL2667368 | 0.94 | GCK (0.48) | GCKKCNH2ALDH1A1PTGDRL3MBTL1 | |
| SCHEMBL2667732 | 0.92 | GCK (0.46) | GCKKCNH2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9070838 | 0.88 | GCK (0.52) | GCKALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9070926 | 0.87 | PRKAA2 (0.46) | GCKKCNH2 | |
| SCHEMBL2667579 | 0.87 | GCK (0.51) | GCKKCNH2L3MBTL1 | |
| SCHEMBL2667687 | 0.87 | GCK (0.51) | GCKKCNH2L3MBTL1 | |
| SCHEMBL2667442 | 0.87 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL9071038 | 0.86 | GCK (0.48) | GCK | |
| SCHEMBL9071013 | 0.85 | GCK (0.49) | GCKKCNH2ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |