Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667444 | 0.89 | F2 (0.41) | GCKF2F10PRSS1PRSS2 | |
| SCHEMBL2667630 | 0.89 | GCK (0.51) | GCKKCNH2 | |
| SCHEMBL9071022 | 0.86 | GCK (0.48) | GCKKCNH2F2F10PRSS1 | |
| SCHEMBL2667646 | 0.85 | GCK (0.46) | GCKKCNH2 | |
| SCHEMBL9070937 | 0.85 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL9071010 | 0.85 | ALDH1A1 (0.44) | GCK | |
| SCHEMBL2667819 | 0.82 | GCK (0.44) | GCKF2F10 | |
| SCHEMBL2667534 | 0.81 | GCK (0.65) | GCK | |
| SCHEMBL9070848 | 0.81 | GCK (0.64) | GCKKCNH2 | |
| SCHEMBL9070853 | 0.81 | GCK (0.55) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |