Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667646 | 0.98 | GCK (0.46) | GCKKCNH2ALDH1A1POLBKMT2A | |
| SCHEMBL9071010 | 0.93 | ALDH1A1 (0.44) | GCKALDH1A1POLBKMT2A | |
| SCHEMBL2667630 | 0.87 | GCK (0.51) | GCKKCNH2 | |
| SCHEMBL9071057 | 0.86 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL9070851 | 0.85 | GCK (0.45) | GCKKCNH2 | |
| SCHEMBL9071022 | 0.84 | GCK (0.48) | GCKKCNH2 | |
| SCHEMBL2667970 | 0.84 | GCK (0.51) | GCKKCNH2 | |
| SCHEMBL9070941 | 0.83 | GCK (0.60) | GCKKCNH2 | |
| SCHEMBL2667727 | 0.82 | ALDH1A1 (0.46) | ALDH1A1POLBKMT2AGAARAB9A | |
| SCHEMBL2667688 | 0.82 | GCK (0.63) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |