Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | GCK | P35557 | 9/20 | 0.51 |
| ▸ | SCD | O00767 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667661 | 0.90 | NPC1 (0.54) | NPC1RAB9AGCKSCDMAPT | |
| SCHEMBL9070867 | 0.90 | SCD (0.56) | NPC1RAB9AGCKSCDMAPT | |
| SCHEMBL9070963 | 0.90 | GCK (0.52) | NPC1RAB9AGCKSCDMAPT | |
| SCHEMBL2667658 | 0.87 | NPC1 (0.57) | NPC1RAB9AGCKSCDMAPT | |
| SCHEMBL2667627 | 0.87 | NPC1 (0.57) | NPC1RAB9AGCKSCDMAPT | |
| SCHEMBL2667628 | 0.87 | NPC1 (0.57) | NPC1RAB9AGCKSCDMAPT | |
| SCHEMBL2668008 | 0.85 | NPC1 (0.51) | NPC1RAB9AGCKSCDMAPT | |
| SCHEMBL2667716 | 0.85 | KDM4E (0.48) | RAB9AGCKHPGD | |
| SCHEMBL9070914 | 0.84 | RAB9A (0.56) | NPC1RAB9AGCKSCDMAPT | |
| SCHEMBL9070919 | 0.82 | GRM5 (0.55) | NPC1RAB9AGCKSCDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |