Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | GCK | P35557 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070864 | 0.90 | NPC1 (0.54) | SCDNPC1RAB9AGCKMEN1 | |
| SCHEMBL9070919 | 0.90 | GRM5 (0.55) | SCDNPC1RAB9AGCKMEN1 | |
| SCHEMBL2667627 | 0.89 | NPC1 (0.57) | SCDNPC1RAB9AGCKMEN1 | |
| SCHEMBL2667628 | 0.89 | NPC1 (0.57) | SCDNPC1RAB9AGCKMEN1 | |
| SCHEMBL2667658 | 0.89 | NPC1 (0.57) | SCDNPC1RAB9AGCKMEN1 | |
| SCHEMBL2667637 | 0.89 | SCD (0.52) | SCDNPC1RAB9AGCKMEN1 | |
| SCHEMBL2667671 | 0.88 | GRM5 (0.48) | SCDNPC1RAB9AGCKMEN1 | |
| SCHEMBL2667619 | 0.88 | NPC1 (0.51) | SCDNPC1RAB9AGCKMEN1 | |
| SCHEMBL2667598 | 0.85 | NPC1 (0.53) | SCDNPC1RAB9AGCKMEN1 | |
| SCHEMBL9070866 | 0.84 | KDM4E (0.47) | SCDRAB9AGCKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |