Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AQP4 | P55087 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667716 | 0.90 | KDM4E (0.48) | KDM4ELMNARAB9AGCKPOLB | |
| SCHEMBL9070916 | 0.90 | ALDH1A1 (0.45) | KDM4ELMNARAB9AGCKPOLB | |
| SCHEMBL2667626 | 0.89 | NOX1 (0.49) | KDM4ELMNARAB9AGCKPOLB | |
| SCHEMBL9070883 | 0.89 | NOX1 (0.49) | KDM4ELMNARAB9AGCKPOLB | |
| SCHEMBL9070891 | 0.89 | NOX1 (0.49) | KDM4ELMNARAB9AGCKPOLB | |
| SCHEMBL2667656 | 0.89 | KDM4E (0.43) | KDM4ELMNARAB9APOLBMEN1 | |
| SCHEMBL2667707 | 0.88 | RAB9A (0.44) | KDM4ELMNARAB9AGCKAQP4 | |
| SCHEMBL2667653 | 0.88 | GCK (0.49) | KDM4ELMNARAB9AGCKAQP4 | |
| SCHEMBL2667598 | 0.85 | NPC1 (0.53) | KDM4ERAB9AGCKSCDHPGD | |
| SCHEMBL9070867 | 0.84 | SCD (0.56) | RAB9AGCKSCDHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |