Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 12/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070819 | 0.86 | RAB9A (0.47) | GCKRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL9070886 | 0.86 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2MAPTPOLB | |
| SCHEMBL9070914 | 0.85 | RAB9A (0.56) | GCKRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL2667498 | 0.83 | SCD (0.51) | RAB9ANPC1SMN1; SMN2SCDMAPT | |
| SCHEMBL9070887 | 0.81 | RAB9A (0.51) | GCKRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL9070823 | 0.79 | GCK (0.54) | GCK | |
| SCHEMBL9070889 | 0.74 | RAB9A (0.44) | GCKRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL9070864 | 0.72 | NPC1 (0.54) | GCKRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL2667643 | 0.72 | RAB9A (0.49) | GCKRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL2667661 | 0.72 | NPC1 (0.54) | GCKRAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |