Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 7/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | CPT1A | P50416 | 9/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 9/20 | 0.43 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667694 | 0.94 | GCK (0.48) | GCKKCNH2F2F10CPT1A | |
| SCHEMBL9070833 | 0.94 | GCK (0.50) | GCKKCNH2F2F10CPT1A | |
| SCHEMBL9071024 | 0.92 | GCK (0.48) | GCKKCNH2 | |
| SCHEMBL9070994 | 0.92 | MAPK1 (0.51) | — | |
| SCHEMBL9070953 | 0.91 | SCD (0.46) | GCKKCNH2CPT1ACPT1BSCD | |
| SCHEMBL2667481 | 0.90 | F2 (0.42) | GCKKCNH2F2F10CPT1A | |
| SCHEMBL9070991 | 0.89 | GCK (0.52) | GCKKCNH2 | |
| SCHEMBL2667529 | 0.87 | ALDH1A1 (0.51) | GCKCPT1ACPT1B | |
| SCHEMBL9070831 | 0.85 | MAPK1 (0.53) | GCKKCNH2 | |
| SCHEMBL2667699 | 0.85 | ALDH1A1 (0.55) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |