Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.50 |
| ▸ | CPT1A | P50416 | 2/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667694 | 0.98 | GCK (0.48) | GCKKCNH2CPT1ACPT1BF2 | |
| SCHEMBL9070992 | 0.94 | GCK (0.45) | GCKKCNH2CPT1ACPT1BF2 | |
| SCHEMBL9070953 | 0.93 | SCD (0.46) | GCKKCNH2CPT1ACPT1B | |
| SCHEMBL9070831 | 0.91 | MAPK1 (0.53) | GCKKCNH2 | |
| SCHEMBL9071058 | 0.91 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL2667969 | 0.90 | GCK (0.51) | GCKKCNH2 | |
| SCHEMBL2667699 | 0.90 | ALDH1A1 (0.55) | GCKKCNH2 | |
| SCHEMBL9070911 | 0.90 | GCK (0.46) | GCKKCNH2CPT1ACPT1BF2 | |
| SCHEMBL9070943 | 0.88 | GCK (0.45) | GCKKCNH2CPT1ACPT1BF2 | |
| SCHEMBL2667389 | 0.86 | ALDH1A1 (0.56) | GCKKCNH2CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |