Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070949 | 0.91 | GCK (0.66) | GCKKCNH2 | |
| SCHEMBL2667788 | 0.90 | GCK (0.71) | GCKKCNH2 | |
| SCHEMBL2667519 | 0.85 | PTGDR (0.56) | GCKKCNH2 | |
| SCHEMBL9070929 | 0.85 | GCK (0.55) | GCKKCNH2 | |
| SCHEMBL2667973 | 0.84 | GCK (0.77) | GCKKCNH2 | |
| SCHEMBL9070905 | 0.83 | GCK (0.64) | GCKKCNH2HPGDSCYP1A2ABCB1 | |
| SCHEMBL2667779 | 0.83 | GCK (0.54) | GCKKCNH2NPC1RAB9AHPGDS | |
| SCHEMBL2667780 | 0.82 | GCK (0.69) | GCKKCNH2 | |
| SCHEMBL2660156 | 0.82 | GCK (0.89) | GCKKCNH2 | |
| SCHEMBL9070990 | 0.82 | GCK (0.60) | GCKKCNH2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |