Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737324 | 0.87 | HDAC6 (0.50) | GAAMAPTRECQL | |
| SCHEMBL2835719 | 0.80 | ALDH1A1 (0.45) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL1477613 | 0.80 | MIF (0.50) | ALDH1A1GAAGFERMAPTMEN1 | |
| SCHEMBL3568864 | 0.79 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTKMT2ARECQL | |
| SCHEMBL1121892 | 0.79 | ALOX15 (0.51) | ALDH1A1GAAGFERMAPTMEN1 | |
| SCHEMBL17680509 | 0.75 | POLB (0.53) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL13605085 | 0.75 | MAPT (0.63) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL19631985 | 0.75 | MAPT (0.49) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL17172491 | 0.75 | ALDH1A1 (0.66) | ALDH1A1GAAKMT2AHDAC1TDP1 | |
| SCHEMBL23033538 | 0.75 | CA12 (0.48) | ALDH1A1GAAGFERMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |