Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.42 |
| ▸ | GIPR | P48546 | 7/20 | 0.42 |
| ▸ | STAT3 | P40763 | 7/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072820 | 0.91 | GCGR (0.42) | GCGRGIPRSTAT3TRPM8 | |
| SCHEMBL2663331 | 0.89 | STAT3 (0.40) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL9072933 | 0.86 | GCGR (0.43) | GCGRGIPRSTAT3 | |
| SCHEMBL2663352 | 0.82 | STAT3 (0.54) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2663358 | 0.80 | STAT3 (0.55) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL4091700 | 0.79 | GCGR (0.56) | GCGRGIPRSTAT3 | |
| SCHEMBL4091698 | 0.79 | GCGR (0.56) | GCGRGIPRSTAT3 | |
| SCHEMBL2663367 | 0.79 | STAT3 (0.47) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2663199 | 0.78 | HDAC1 (0.37) | HDAC1HDAC8HDAC6TRPM8 | |
| SCHEMBL2663582 | 0.78 | STAT3 (0.45) | GCGRGIPRSTAT3OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |