Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072822 | 0.83 | TPH1 (0.42) | MAPTSMN1; SMN2RAB9ANPC1CNR2 | |
| SCHEMBL2663176 | 0.80 | NPC1 (0.41) | MAPTSMN1; SMN2RAB9ANPC1CNR2 | |
| SCHEMBL9072933 | 0.79 | GCGR (0.43) | — | |
| SCHEMBL4092859 | 0.78 | LMNA (0.43) | LMNA | |
| SCHEMBL4092863 | 0.78 | LMNA (0.43) | LMNA | |
| SCHEMBL9072804 | 0.78 | GCGR (0.42) | HDAC1HDAC8HDAC6TRPM8 | |
| SCHEMBL2663331 | 0.77 | STAT3 (0.40) | HDAC1HDAC6 | |
| SCHEMBL2663383 | 0.76 | KDM4E (0.37) | MAPTSMN1; SMN2RAB9ANPC1TPH1 | |
| SCHEMBL2663329 | 0.71 | GCGR (0.40) | MAPTSMN1; SMN2RAB9AALDH1A1TRPM8 | |
| SCHEMBL2663352 | 0.67 | STAT3 (0.54) | HDAC1HDAC8HDAC6HDAC3HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |