SCHEMBL9072944

SCHEMBL9072944

N=C(/N=N\N)NC(=O)c1ccc(CN(C(=O)CCCc2ccc([N+](=O)O)cc2)c2ccc(C3CCCCC3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GCGR P47871 9/20 0.41
STAT3 P40763 10/20 0.37
GIPR P48546 7/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2663582 0.79 STAT3 (0.45) GCGRSTAT3GIPR
SCHEMBL2663060 0.77 GCGR (0.54) GCGRSTAT3GIPR
SCHEMBL2663171 0.74 GCGR (0.55) GCGRSTAT3GIPR
SCHEMBL9072681 0.74 GCGR (0.43) GCGRSTAT3GIPR
SCHEMBL9072918 0.74 GCGR (0.67) GCGRSTAT3GIPR
SCHEMBL2663327 0.73 GCGR (0.52) GCGRSTAT3GIPR
SCHEMBL13800428 0.73 GCGR (0.52) GCGRSTAT3GIPR
SCHEMBL9072667 0.73 GCGR (0.47) GCGRSTAT3GIPR
SCHEMBL9072943 0.72 GCGR (0.42) GCGRSTAT3GIPR
SCHEMBL2663062 0.72 GCGR (0.69) GCGRSTAT3GIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000069810-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2000-11-23 WO disclosed