Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786967 | 0.82 | SYK (0.51) | L3MBTL1MAPTPOLBMAPK1SIGMAR1 | |
| SCHEMBL17786969 | 0.82 | SYK (0.51) | L3MBTL1MAPTPOLBMAPK1SIGMAR1 | |
| SCHEMBL9437268 | 0.80 | LMNA (0.50) | L3MBTL1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL17599919 | 0.79 | CYP3A4 (0.59) | CYP3A4L3MBTL1MAPTPOLBMAPK1 | |
| SCHEMBL2598790 | 0.79 | SYK (0.59) | L3MBTL1MAPTKMT2AMEN1CA1 | |
| SCHEMBL13334305 | 0.79 | MAPT (0.55) | CYP3A4L3MBTL1MAPTPOLBMAPK1 | |
| SCHEMBL4889499 | 0.78 | CA1 (0.65) | CYP3A4L3MBTL1SIGMAR1CA1CA2 | |
| SCHEMBL5057110 | 0.78 | CYP3A4 (0.58) | CYP3A4L3MBTL1MAPTPOLBMAPK1 | |
| SCHEMBL15679441 | 0.78 | MAPT (0.64) | CYP3A4L3MBTL1MAPTPOLBMAPK1 | |
| SCHEMBL13090607 | 0.78 | MAPT (0.64) | CYP3A4L3MBTL1MAPTPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5493053-A | Method for preparing desferrioxamine B and homologs thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1996-02-20 | — | — | US | disclosed |