Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.55 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.55 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119838 | 1.00 | AKT1 (0.61) | AKT1MAPTLMNARECQLPLIN1 | |
| SCHEMBL30924824 | 0.92 | AKT1 (0.57) | AKT1MAPTLMNARECQLPLIN1 | |
| SCHEMBL21965089 | 0.84 | AKT1 (0.48) | AKT1MAPTLMNARECQLPLIN1 | |
| SCHEMBL22590637 | 0.84 | AKT1 (0.48) | AKT1MAPTLMNARECQLPLIN1 | |
| SCHEMBL2954318 | 0.81 | MAPT (0.70) | AKT1MAPTLMNARECQLPLIN1 | |
| SCHEMBL11073619 | 0.81 | MAPT (0.70) | AKT1MAPTLMNARECQLPLIN1 | |
| SCHEMBL2954324 | 0.81 | MAPT (0.70) | AKT1MAPTLMNARECQLPLIN1 | |
| SCHEMBL3040776 | 0.80 | ALDH1A1 (0.60) | AKT1MAPTLMNARECQLPLIN1 | |
| SCHEMBL3040779 | 0.80 | ALDH1A1 (0.60) | AKT1MAPTLMNARECQLPLIN1 | |
| SCHEMBL10534017 | 0.79 | ALDH1A1 (0.69) | MAPTLMNAMAOBCYP1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111495289-B | Gas-liquid two-phase continuous reaction device and preparation method of sorbol | 肇庆市高要华新香料有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-111495289-A | Gas-liquid two-phase continuous reaction device and preparation method of sorbol | 肇庆市高要华新香料有限公司 | 2020-08-07 | — | — | CN | disclosed |
| EP-2133099-B1 | Conjugated biological molecules and their preparation | POLYTHERICS LTD (GB) | 2017-04-19 | — | — | EP | disclosed |
| US-9439974-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2016-09-13 | — | — | US | disclosed |
| EP-2253330-B1 | Conjugated biological molecules and their preparation | POLYTHERICS LTD (GB) | 2015-08-19 | — | — | EP | disclosed |
| EP-2277550-B1 | Process for the preparation of conjugated biological molecules. | POLYTHERICS LTD (GB) | 2015-04-29 | — | — | EP | disclosed |
| US-20140369960-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | ABZENA (CAMBRIDGE) LIMITED (GB) | 2014-12-18 | — | — | US | disclosed |
| US-8816051-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2014-08-26 | — | — | US | disclosed |
| US-20110182855-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | POLYTHERICS LIMITED (GB) | 2011-07-28 | — | — | US | disclosed |
| US-7939630-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2011-05-10 | — | — | US | disclosed |
| WO-2004083266-A1 | OLEFIN COPOLYMERS CONTAINING HYDROLYTICALLY CLEAVABLE LINKAGES AND USE THEREOF IN DEGRADABLE PRODUCTS | SRI INTERNATIONAL (US) | 2004-09-30 | — | — | WO | disclosed |
| US-20030236371-A1 | Olefin copolymers containing hydrolytically cleavable linkages and use thereof in degradable products | SRI INTERNATIONAL | 2003-12-25 | — | — | US | disclosed |
| EP-0802804-B1 | Biodegradable polymer-containing compositions | PROCTER & GAMBLE (US) | 2002-04-03 | — | — | EP | disclosed |
| US-5759569-A | CONJUGATED DIENE POLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0802804-A1 | BIODEGRADABLE ARTICLES MADE FROM CERTAIN TRANS-POLYMERS AND BLENDS THEREOF WITH OTHER BIODEGRADABLE COMPONENTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021475-A1 | BIODEGRADABLE ARTICLES MADE FROM CERTAIN TRANS-POLYMERS AND BLENDS THEREOF WITH OTHER BIODEGRADABLE COMPONENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-18 | — | — | WO | disclosed |
| US-4080388-A | Phenyl substituted-hexene-(3)-diol-(1,6) | STUDIENGESELLSCHAFT KOHLE MBH (DT) | 1978-03-21 | — | — | US | disclosed |
| US-4054610-A | INTERMEDIATE FOR PRODUCTION OF POLYENES | STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) | 1977-10-18 | — | — | US | disclosed |
| US-3954887-A | PHENYL SUBSTITUTED UNSATURATED DIOLS | STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) | 1976-05-04 | — | — | US | disclosed |
| US-3839311-A | POLYMER PRO-OXIDANT COMPRISING HYDROXY-SUBSTITUTED 2,4-PENTADIENOPHENONES | PHILLIPS PETROLEUM CO | 1974-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140369960-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | F13B, F13A1, ZYX | AKT1 4379/4885MAPT 4472/4885LMNA 543/4885 |
| US-20110182855-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | F13B, ZYX, F13A1 | AKT1 4162/4885MAPT 4643/4885LMNA 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.