Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23243665 | 0.95 | DGKA (0.59) | DGKAPLA2G4BHSD17B10DNM1NAAA | |
| SCHEMBL17364480 | 0.91 | DGKA (0.66) | DGKAPLA2G4BHSD17B10DNM1NAAA | |
| SCHEMBL29027350 | 0.85 | DGKA (0.58) | DGKAPLA2G4BHSD17B10DNM1NAAA | |
| SCHEMBL10338675 | 0.85 | DGKA (0.53) | DGKAPLA2G4BHSD17B10DNM1NAAA | |
| SCHEMBL28421172 | 0.85 | NAAA (0.58) | DGKAPLA2G4BHSD17B10DNM1NAAA | |
| SCHEMBL23921183 | 0.85 | NAAA (0.58) | DGKAPLA2G4BHSD17B10DNM1NAAA | |
| SCHEMBL31127509 | 0.85 | NAAA (0.58) | DGKAPLA2G4BHSD17B10DNM1NAAA | |
| SCHEMBL9763789 | 0.85 | NAAA (0.58) | DGKAPLA2G4BHSD17B10DNM1NAAA | |
| SCHEMBL17107450 | 0.85 | NAAA (0.58) | DGKAPLA2G4BHSD17B10DNM1NAAA | |
| SCHEMBL29581959 | 0.85 | DGKA (0.58) | DGKAPLA2G4BHSD17B10DNM1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470041-B1 | Process for the preparation of a rubber having polymer bound functionality | GOODYEAR TIRE & RUBBER (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0470041-A1 | Process for the preparation of a rubber having polymer bound functionality | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5073592-A | Oxidation resistant | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-12-17 | — | — | US | disclosed |