SCHEMBL907451

SCHEMBL907451

C=CC(=O)N(CC)CCC[Si](C)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 2/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17359401 0.86 ZDHHC20 (0.36) ZDHHC20ZDHHC2
SCHEMBL907327 0.86 ZDHHC20 (0.41) ZDHHC20ZDHHC2CA12CA1CA9
SCHEMBL4375377 0.82 ZDHHC20 (0.30) ZDHHC20ZDHHC2
SCHEMBL29311651 0.82 ZDHHC20 (0.35) ZDHHC20ZDHHC2
SCHEMBL4372158 0.81
SCHEMBL17049698 0.80 ZDHHC20 (0.33) ZDHHC20ZDHHC2
SCHEMBL9764016 0.79 ZDHHC20 (0.41) ZDHHC20ZDHHC2
SCHEMBL633117 0.79 ZDHHC20 (0.51) ZDHHC20ZDHHC2CA12CA1CA9
SCHEMBL16776772 0.79 ZDHHC20 (0.56) ZDHHC20ZDHHC2CA12CA1CA9
SCHEMBL907484 0.78 CA12 (0.32) CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3556731-A1 METHOD FOR THE CHEMICAL MODIFICATION OF METAL OXIDE SURFACES Justus-Liebig-Universität Gießen (DE) 2019-10-23 EP disclosed
US-8367748-B2 Surface-modified fillers IVOCLAR VIVADENT AG (LI) 2013-02-05 US disclosed
US-8367748-B2 Surface-modified fillers IVOCLAR VIVADENT AG (LI) 2013-02-05 US disclosed
EP-2277496-A1 Dental material containing surface-modified fillers Ivoclar Vivadent AG (LI) 2011-01-26 EP disclosed
EP-1716836-B1 Surface-modified fillers IVOCLAR VIVADENT AG (LI) 2011-01-19 EP disclosed
EP-1716836-A1 Surface-modified fillers Ivoclar Vivadent AG (LI) 2006-11-02 EP disclosed
US-20060247329-A1 Surface-modified fillers IVOCLAR VIVADENT AG (LI) 2006-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247329-A1 Surface-modified fillers MSR1, HRH4, OR10J3 ZDHHC20 1730/4885ZDHHC2 3218/4885CA12 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.