SCHEMBL4375377

SCHEMBL4375377

C=CC(=O)N(CCC[Si](C)(OC)OC)C(=O)C=C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4372158 0.85
SCHEMBL907451 0.82 ZDHHC20 (0.40) ZDHHC20ZDHHC2
SCHEMBL17359401 0.81 ZDHHC20 (0.36) ZDHHC20ZDHHC2
SCHEMBL29311651 0.76 ZDHHC20 (0.35) ZDHHC20ZDHHC2
SCHEMBL5081258 0.76 ALDH1A1 (0.33)
SCHEMBL17049698 0.75 ZDHHC20 (0.33) ZDHHC20ZDHHC2
SCHEMBL1305038 0.73 ALDH1A1 (0.37)
SCHEMBL13862588 0.72 ZDHHC20 (0.43) ZDHHC20ZDHHC2
SCHEMBL13862593 0.72 ZDHHC20 (0.43) ZDHHC20ZDHHC2
SCHEMBL20115416 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383470-B1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2009-06-17 EP disclosed
EP-1383469-B1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2006-02-15 EP disclosed
EP-1383860-B1 FABRIC CARE COMPOSITIONS UNILEVER PLC (GB) 2005-10-12 EP disclosed
US-6767883-B2 Fabric care compositions UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. 2004-07-27 US disclosed
US-6696051-B2 CONTAINING CORE PARTICLES HAVING A D3,2 AVERAGE PARTICLE SIZE OF 10-700 NM, AND COATED WITH COVALENTLY BONDED SILICONE POLYMER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
US-6696050-B2 COATED PARTICLES COMPRISING (A) A SOLID CORE HAVING A D3, 2 AVERAGE PARTICLE SIZE IN THE RANGE FROM 10 TO 700 NM, AND (B) A COATING POLYMER COVALENTLY BONDED TO THE SOLID CORE; E.G., SOLID SILICA CORES AND POLYSTYRENE COATING POLYMER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
US-20030095943-A1 Hair treatment compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-05-22 US disclosed
US-20030012757-A1 Hair treatment compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-01-16 US disclosed
US-20020192367-A1 Fabric care compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-12-19 US disclosed
EP-0433727-B1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE (JP) 1995-08-02 EP disclosed
EP-0433906-B1 Thermoplastic resin and process for producing the same TOSHIBA SILICONE (JP) 1995-07-26 EP disclosed
US-5218014-A Graft polymer formed by graft polymerization of vinyl monomer onto colloidal silica core silicone shell particles TOSHIBA SILICONE CO., LTD. (JP) 1993-06-08 US disclosed
US-5188899-A SILICA-CORE SILICONE-SHELL PARTICLES, EMULSION CONTAINING THE SAME DISPERSED THEREIN, AND PROCESS FOR PRODUCING THE EMULSION TOSHIBA SILICONE CO., LTD. (JP) 1993-02-23 US disclosed
EP-0433906-A2 Thermoplastic resin and process for producing the same TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0433727-A1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030095943-A1 Hair treatment compositions SPTLC3, HACD3, C18orf63 ZDHHC20 116/4885ZDHHC2 248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.