SCHEMBL9074879 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	ALOX5	P09917	7/20	0.32

▸	MAPT	P10636	3/20	0.32

▸	NPC1	O15118	2/20	0.32

▸	NFKB1	P19838	2/20	0.32

▸	RAB9A	P51151	2/20	0.32

▸	NFKB2	Q00653	2/20	0.32

▸	RELA	Q04206	2/20	0.32

▸	MEN1	O00255	1/20	0.32

▸	ALDH1A1	P00352	1/20	0.32

▸	KMT2A	Q03164	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9074018	0.91	ALDH1A1 (0.33)	ALOX5MAPTNPC1NFKB1RAB9A
SCHEMBL9077133	0.88	HTT (0.33)	ALOX5
SCHEMBL9076846	0.88	HTT (0.33)	ALOX5
SCHEMBL9077130	0.88	HTT (0.33)	ALOX5
SCHEMBL9076849	0.88	HTT (0.33)	ALOX5
SCHEMBL9077136	0.88	HTT (0.33)	ALOX5
SCHEMBL9046459	0.84	ALOX5 (0.35)	ALOX5
SCHEMBL9051191	0.84	ALOX5 (0.35)	ALOX5
SCHEMBL9075774	0.84	ALOX5 (0.38)	ALOX5
SCHEMBL9045913	0.78	ALOX5 (0.53)	ALOX5MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5482966-A	LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS	ZENECA LIMITED (GB)	1996-01-09	—	—	US	disclosed
US-5332757-A	Enzyme inhibitors	ZENECA LIMITED (GB)	1994-07-26	—	—	US	disclosed