Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | EBP | Q15125 | 2/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9077499 | 0.90 | SIGMAR1 (1.00) | SIGMAR1EBPTMEM97EBPL | |
| Oxalic Acid SCHEMBL9077778 | 0.89 | SIGMAR1 (0.81) | SIGMAR1EBPTMEM97EBPL | |
| Oxalic Acid SCHEMBL9077864 | 0.82 | SIGMAR1 (0.74) | SIGMAR1KDM4ELMNATSHR | |
| Oxalic Acid SCHEMBL9077392 | 0.80 | KDM4E (0.58) | SIGMAR1KDM4ETDP1TSHR | |
| Oxalic Acid SCHEMBL9077129 | 0.79 | KDM4E (0.58) | KDM4E | |
| Hydrochloric Acid SCHEMBL9077445 | 0.78 | SIGMAR1 (0.74) | SIGMAR1 | |
| SCHEMBL8075010 | 0.78 | SIGMAR1 (0.89) | SIGMAR1EBPTMEM97EBPL | |
| Hydrochloric Acid SCHEMBL8088180 | 0.77 | SIGMAR1 (0.87) | SIGMAR1EBPTMEM97EBPL | |
| SCHEMBL13803105 | 0.76 | SYK (0.55) | SIGMAR1KDM4ETDP1LMNATSHR | |
| SCHEMBL8731740 | 0.76 | SIGMAR1 (0.64) | SIGMAR1EBPTMEM97LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |