Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL9074395 | 0.90 | RAB9A (0.49) | RAB9ANPC1PKMKDM4ELMNA | |
| SCHEMBL84647 | 0.82 | — | — | |
| SCHEMBL30212452 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7170102 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL7984432 | 0.80 | — | — | |
| Iodide SCHEMBL3384560 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL5753035 | 0.80 | RAB9A (0.47) | RAB9ANPC1PKMKDM4ELMNA | |
| Nitrous Acid SCHEMBL3384483 | 0.79 | TP53 (0.53) | RAB9ANPC1PKMKDM4ELMNA | |
| Acetic Acid SCHEMBL28856321 | 0.79 | NPC1 (0.58) | RAB9ANPC1PKMKDM4ELMNA | |
| SCHEMBL9075216 | 0.79 | MDM2 (0.41) | RAB9APKMKDM4ELMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583122-A | TREATING DISEASES ASSOCIATED WITH ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0230068-B1 | USE OF A GEMINAL DIPHOSPHONIC ACID COMPOUND TO PREPARE A MEDICAMENT | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-07-15 | — | — | EP | disclosed |
| EP-0186405-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING GEMINAL DIPHOSPHONATES | THE PROCTER & GAMBLE COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4902679-A | TREATING BONE DISORDERS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0186405-A2 | Pharmaceutical compositions containing geminal diphosphonates | THE PROCTER & GAMBLE COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |