Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL9075212 | 0.88 | MDM2 (0.46) | MDM2CTSDKDM4EL3MBTL1TAAR1 | |
| SCHEMBL10340488 | 0.80 | TSHR (0.58) | TAAR1EPHX1TSHRRAB9AALDH1A1 | |
| SCHEMBL9075007 | 0.79 | RAB9A (0.44) | KDM4ERAB9AALDH1A1TP53HIF1A | |
| SCHEMBL84825 | 0.78 | — | — | |
| Bicarbonate SCHEMBL23093808 | 0.77 | MDM2 (0.54) | MDM2CTSDKDM4EL3MBTL1TAAR1 | |
| Hydrochloric Acid SCHEMBL27865056 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28137223 | 0.76 | CTSD (0.55) | MDM2CTSDKDM4EL3MBTL1TAAR1 | |
| Fluoride SCHEMBL29031926 | 0.76 | — | — | |
| SCHEMBL9636978 | 0.73 | KMT2A (0.38) | ALDH1A1HSD17B10TP53MEN1KMT2A | |
| Pyridine 4-Methanol SCHEMBL9073924 | 0.71 | ALDH1A1 (0.40) | TSHRALDH1A1RECQLHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583122-A | TREATING DISEASES ASSOCIATED WITH ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0230068-B1 | USE OF A GEMINAL DIPHOSPHONIC ACID COMPOUND TO PREPARE A MEDICAMENT | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-07-15 | — | — | EP | disclosed |
| EP-0186405-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING GEMINAL DIPHOSPHONATES | THE PROCTER & GAMBLE COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4902679-A | TREATING BONE DISORDERS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0186405-A2 | Pharmaceutical compositions containing geminal diphosphonates | THE PROCTER & GAMBLE COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |