Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.51 |
| ▸ | FNTB | P49356 | 3/20 | 0.51 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 4/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365981 | 1.00 | FNTA (0.51) | FNTAFNTBNR1D1MMEACE | |
| SCHEMBL8329445 | 0.83 | FNTA (0.59) | FNTAFNTBNR1D1MMEACE | |
| SCHEMBL8329449 | 0.83 | FNTA (0.59) | FNTAFNTBNR1D1MMEACE | |
| SCHEMBL9074343 | 0.80 | FNTA (0.66) | FNTAFNTBNR1D1MMEACE | |
| SCHEMBL8588406 | 0.80 | FNTA (0.66) | FNTAFNTBNR1D1MMEACE | |
| SCHEMBL8328748 | 0.74 | FNTA (0.56) | FNTAFNTBNR1D1MMEACE | |
| SCHEMBL8303881 | 0.74 | FNTA (0.56) | FNTAFNTBNR1D1MMEACE | |
| SCHEMBL18942412 | 0.74 | TDP1 (0.62) | PPARGPPARACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8334300 | 0.72 | FNTA (0.61) | FNTAFNTBNR1D1MMEACE | |
| SCHEMBL8536367 | 0.71 | CTSS (0.45) | FNTAFNTBNR1D1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576293-A | TETRAPEPTIDES, ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 1996-11-19 | — | — | US | disclosed |
| WO-1995009001-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1995-04-06 | — | — | WO | disclosed |