Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459894 | 0.82 | FDPS (0.72) | FDPSALDH1A1KCNA5SMN1; SMN2HPGD | |
| SCHEMBL1904611 | 0.81 | FDPS (1.00) | FDPSALDH1A1KCNA5SMN1; SMN2 | |
| SCHEMBL9074140 | 0.79 | FDPS (0.68) | FDPSALDH1A1KCNA5SMN1; SMN2HPGD | |
| SCHEMBL9075279 | 0.79 | FDPS (0.68) | FDPSALDH1A1KCNA5SMN1; SMN2NPC1 | |
| SCHEMBL8712686 | 0.79 | FDPS (0.97) | FDPSALDH1A1KCNA5SMN1; SMN2 | |
| SCHEMBL8712700 | 0.79 | FDPS (0.97) | FDPSALDH1A1KCNA5SMN1; SMN2 | |
| SCHEMBL8769065 | 0.77 | FDPS (0.64) | FDPSALDH1A1KCNA5SMN1; SMN2HPGD | |
| SCHEMBL7852971 | 0.76 | FDPS (0.67) | FDPSALDH1A1KCNA5SMN1; SMN2POLB | |
| SCHEMBL14817592 | 0.76 | FDPS (0.67) | FDPSALDH1A1KCNA5SMN1; SMN2POLB | |
| SCHEMBL11952611 | 0.76 | FDPS (0.82) | FDPSALDH1A1KCNA5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583122-A | TREATING DISEASES ASSOCIATED WITH ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| US-5283057-A | Risedronate in oral compositions | THE PROCTER & GAMBLE COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0186405-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING GEMINAL DIPHOSPHONATES | THE PROCTER & GAMBLE COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| EP-0186405-A2 | Pharmaceutical compositions containing geminal diphosphonates | THE PROCTER & GAMBLE COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |