Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 6/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073125 | 0.96 | CYP2C9 (0.37) | CYP2C9MEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9073110 | 0.95 | MAPT (0.37) | CYP2C9MEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9075604 | 0.95 | MAPT (0.37) | CYP2C9MEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9074795 | 0.95 | MAPT (0.37) | CYP2C9MEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9074856 | 0.93 | CYP2C9 (0.45) | CYP2C9MEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9073214 | 0.89 | KIF11 (0.38) | CYP2C9ALDH1A1LMNAMAPTKIF11 | |
| SCHEMBL9075123 | 0.88 | CYP2C9 (0.36) | CYP2C9MEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL16104424 | 0.86 | CYP2C9 (0.42) | CYP2C9MEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9073625 | 0.85 | CYP2C9 (0.36) | CYP2C9MEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9074106 | 0.84 | DGAT1 (0.36) | CYP2C9MEN1MAPK1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465621-B1 | PARTIALLY FLUORINATED COMPOUNDS | MERCK PATENT GMBH (DE) | 1996-11-13 | — | — | EP | disclosed |
| WO-1991011418-A1 | PARTIALLY FLUORINATED COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-08-08 | — | — | WO | disclosed |