SCHEMBL9075274

SCHEMBL9075274

O=C(O)Cc1cc(Cl)ccc1OCCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.52
HTR2C P28335 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR2B P41595 1/20 0.50
HTR6 P50406 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9078395 0.93 CHRM1 (0.51) CHRM1MAPT
SCHEMBL9077989 0.89 CHRM1 (0.52) CHRM1HTR2CSLC6A4HTR2BHTR6
SCHEMBL2110600 0.86 PTGER1 (0.62) CHRM1
SCHEMBL9078338 0.85
SCHEMBL9077348 0.83 CYP11B1 (0.49)
SCHEMBL8733926 0.83 HTR2C (0.50) HTR2CSLC6A4HTR2BHTR6
SCHEMBL9077267 0.81 MTNR1B (0.66)
SCHEMBL9077759 0.81
SCHEMBL27689470 0.80 HTR2C (0.52) HTR2CSLC6A4HTR2BHTR6
SCHEMBL9077745 0.80 HTR2C (0.52) HTR2CSLC6A4HTR2BHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5495046-A PSYCHOLOGICAL DISORDERS TAISHO PHARMACEUTICAL CO., LTD. (JP) 1996-02-27 US disclosed
EP-0641766-A1 ALKOXYPHENYLALKYLAMINE DERIVATIVE TAISHO PHARMACEUTICAL CO. LTD (JP) 1995-03-08 EP disclosed