Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.45 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077270 | 0.93 | PTGDR2 (0.49) | PTGDR2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL8420618 | 0.89 | HTR2C (0.50) | HTR2CSLC6A4HTR2BPTGDR2HTR6 | |
| SCHEMBL8734857 | 0.88 | FFAR1 (0.54) | HTR2CSLC6A4HTR2BPTGDR2HTR6 | |
| SCHEMBL2537002 | 0.86 | USP28 (0.60) | PTGDR2ALDH1A1HTTLMNAUSP28 | |
| SCHEMBL9077348 | 0.83 | CYP11B1 (0.49) | PTGESALOX5PPARGMTNR1AMTNR1B | |
| SCHEMBL9075274 | 0.83 | CHRM1 (0.52) | HTR2CSLC6A4HTR2BHTR6 | |
| SCHEMBL9077267 | 0.81 | MTNR1B (0.66) | MEN1KMT2APTGESALOX5PPARG | |
| SCHEMBL548139 | 0.80 | USP28 (0.54) | ALDH1A1HTTUSP28USP25PTGER1 | |
| SCHEMBL9075485 | 0.80 | MCHR1 (0.49) | MEN1KMT2AALOX5PPARG | |
| Oxalic Acid SCHEMBL8197986 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641766-B1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |