Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.59 |
| ▸ | TTPA | P49638 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521181 | 0.88 | MAPT (0.58) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL10643062 | 0.85 | MAPT (0.56) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL10641198 | 0.85 | MAPT (0.56) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL10641411 | 0.84 | ALOX5 (0.57) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL10641397 | 0.84 | ALOX5 (0.57) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL10641508 | 0.84 | ALOX5 (0.57) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL23867134 | 0.84 | MAPT (0.63) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL8935467 | 0.84 | NR1I2 (0.65) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL4271100 | 0.84 | NR1I2 (0.65) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL8935461 | 0.84 | NR1I2 (0.65) | MAPTLMNAUSP2CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508450-A | INHIBITORY EFFECT ON MAILLARD REACTION AND ANTIOXIDIZING EFFECT; TREATS OR PREVENTS DIABETIC COMPLICATIONS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5384414-A | Compounds with guanidine groups | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-24 | — | — | US | disclosed |