Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.64 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | EBP | Q15125 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8730455 | 0.94 | SIGMAR1 (0.62) | LTB4RLTB4R2KMT2AGAAALDH1A1 | |
| SCHEMBL9077917 | 0.86 | SLC2A1 (0.52) | LTB4RLTB4R2SIGMAR1ALOX5PTGES | |
| SCHEMBL9076148 | 0.86 | SLC2A1 (0.52) | LTB4RLTB4R2SIGMAR1ALOX5PTGES | |
| SCHEMBL31011346 | 0.86 | NPC1 (0.63) | KMT2ACA5AGAAALDH1A1TSHR | |
| SCHEMBL1114985 | 0.86 | NPC1 (0.63) | KMT2ACA5AGAAALDH1A1TSHR | |
| SCHEMBL4070157 | 0.84 | CA5A (0.61) | LTB4RLTB4R2KMT2ACA5AGAA | |
| SCHEMBL11435026 | 0.84 | CA5A (0.61) | LTB4RLTB4R2CA5AGAAALDH1A1 | |
| SCHEMBL10461053 | 0.83 | CA5A (0.59) | LTB4RLTB4R2CA5AGAAALDH1A1 | |
| SCHEMBL12327982 | 0.83 | CA5A (0.59) | LTB4RLTB4R2CA5AGAAALDH1A1 | |
| SCHEMBL8731740 | 0.82 | SIGMAR1 (0.64) | KMT2ASIGMAR1EBPTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |