Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605555 | 0.87 | TSHR (0.36) | TSHR | |
| SCHEMBL6822982 | 0.86 | LMNA (0.34) | MMP9LMNATSHR | |
| SCHEMBL4303707 | 0.84 | TSHR (0.40) | LMNATSHR | |
| SCHEMBL598055 | 0.80 | LMNA (0.40) | LMNATSHR | |
| SCHEMBL12274150 | 0.79 | MMP9 (0.33) | MMP9 | |
| SCHEMBL8367717 | 0.78 | MMP9 (0.36) | MMP9TSHR | |
| SCHEMBL14480913 | 0.78 | TSHR (0.38) | MMP9TSHR | |
| SCHEMBL29104150 | 0.77 | LMNA (0.37) | LMNA | |
| SCHEMBL18638803 | 0.76 | MMP9 (0.35) | MMP9TSHR | |
| SCHEMBL25785610 | 0.76 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534529-A | Substituted aromatic amides and ureas derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 1996-07-09 | — | — | US | disclosed |