Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | XIAP | P98170 | 2/20 | 0.40 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076469 | 0.91 | F2 (0.51) | F2PRSS1PRSS2PRSS3TMPRSS11D | |
| SCHEMBL7334169 | 0.91 | F2 (0.53) | F2PRSS1PRSS2PRSS3TMPRSS11D | |
| SCHEMBL9073832 | 0.88 | F2 (0.54) | F2PRSS1PRSS2PRSS3TMPRSS11D | |
| SCHEMBL7346760 | 0.88 | F2 (0.54) | F2PRSS1PRSS2PRSS3TMPRSS11D | |
| SCHEMBL7337918 | 0.88 | F2 (0.51) | F2PRSS1XIAPTMPRSS11DOPRM1 | |
| SCHEMBL9075660 | 0.88 | F2 (0.51) | F2PRSS1XIAPTMPRSS11D | |
| SCHEMBL7338554 | 0.87 | F2 (0.53) | F2PRSS1PRSS2PRSS3TMPRSS11D | |
| SCHEMBL7341166 | 0.87 | F2 (0.53) | F2PRSS1PRSS2PRSS3TMPRSS11D | |
| SCHEMBL9075667 | 0.87 | F2 (0.50) | F2PRSS1PRSS2PRSS3TMPRSS11D | |
| SCHEMBL7337494 | 0.87 | F2 (0.53) | F2PRSS1PRSS2PRSS3XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |