SCHEMBL9075787

SCHEMBL9075787

CCCC(c1ccccc1C)c1ccccc1OC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
POLB P06746 3/20 0.39
HTT P42858 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
RECQL P46063 1/20 0.38
TSHR P16473 1/20 0.37
GLA P06280 1/20 0.37
ATM Q13315 1/20 0.37
CYP19A1 P11511 1/20 0.37
ALDH1A1 P00352 1/20 0.36
PTGES O14684 1/20 0.36
ALOX5 P09917 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
CTSA P10619 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9075783 0.91 TDP1 (0.40) TDP1L3MBTL1POLBHTTNPSR1
SCHEMBL9076618 0.85 TSHR (0.40) TDP1L3MBTL1POLBHTTNPSR1
SCHEMBL6745681 0.85 MEN1 (0.40) TDP1L3MBTL1POLBHTTNPSR1
SCHEMBL9330275 0.80 CYP19A1 (0.49) POLBNPSR1TSHRCYP19A1ESR1
SCHEMBL25276943 0.80 KDM4E (0.44) TDP1L3MBTL1POLBHTTNPSR1
Ammonia Solution, Strong SCHEMBL5725582 0.79 CYP19A1 (0.47) POLBNPSR1TSHRCYP19A1ESR1
SCHEMBL25272705 0.78 ESR1 (0.40) TDP1L3MBTL1POLBHTTNPSR1
SCHEMBL9076605 0.77 TSHR (0.40) TDP1L3MBTL1POLBHTTNPSR1
SCHEMBL6745678 0.76 KDM4E (0.41) TDP1L3MBTL1POLBHTTNPSR1
SCHEMBL15104783 0.75 PTGS2 (0.38) TDP1L3MBTL1POLBHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322919-A Transesterification in an inert solvent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-06-21 US claimed
EP-0434998-B1 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof G E PLASTICS JAPAN LTD (JP) 1996-02-07 EP disclosed
US-5459225-A Ester interchange in antioxidant presence IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-10-17 US disclosed
US-5349042-A Ester interchange and dechlorination with carbonation IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-20 US disclosed
US-5322919-A Transesterification in an inert solvent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-06-21 US disclosed
EP-0561363-A2 Process for producing polycarbonate IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-09-22 EP disclosed
US-5187242-A Workable molding materials containing aliphatic carboxylic acids and aromatic diols as monomers, impact strenth, transparency GENERAL ELECTRIC COMPANY (US) 1993-02-16 US disclosed
EP-0488182-A2 Process for producing a polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0434998-A2 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof GE PLASTICS JAPAN LIMITED (JP) 1991-07-03 EP disclosed