SCHEMBL6745681

SCHEMBL6745681

CCCC(c1ccccc1)c1ccccc1OC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
KDM4E B2RXH2 3/20 0.40
RECQL P46063 1/20 0.40
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
GLA P06280 1/20 0.39
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
POLB P06746 5/20 0.38
PTGS2 P35354 3/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
AOC3 Q16853 1/20 0.37
HPGD P15428 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
FFAR1 O14842 1/20 0.37
ESR1 P03372 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6745678 0.91 KDM4E (0.41) MEN1KMT2AKDM4ERECQLCHRM2
SCHEMBL9075787 0.85 TDP1 (0.40) MEN1KMT2AKDM4ERECQLL3MBTL1
SCHEMBL9076618 0.85 TSHR (0.40) MEN1KMT2AKDM4ERECQLL3MBTL1
SCHEMBL25276943 0.83 KDM4E (0.44) MEN1KMT2AKDM4ERECQLL3MBTL1
SCHEMBL25336789 0.82 MAPT (0.41) MEN1KMT2AKDM4ERECQLL3MBTL1
SCHEMBL25338308 0.82 L3MBTL1 (0.41) MEN1KMT2ARECQLL3MBTL1GLA
SCHEMBL6330054 0.82 MEN1 (0.51) MEN1KMT2AL3MBTL1POLBHTT
SCHEMBL15899436 0.81 HPGD (0.43) MEN1KMT2AKDM4EL3MBTL1POLB
SCHEMBL25338201 0.80 PTGS2 (0.44) MEN1KMT2AKDM4ERECQLL3MBTL1
SCHEMBL15899542 0.79 L3MBTL1 (0.44) MEN1KMT2AKDM4EL3MBTL1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2774950-B1 RESIN COMPOSITION AND MOLDED BODY MIDORI ANZEN CO LTD (JP) 2019-03-27 EP disclosed
US-10093796-B2 Resin composition and molded body MIDORI ANZEN CO., LTD. (JP) 2018-10-09 US disclosed
US-20140296422-A1 RESIN COMPOSITION AND MOLDED BODY MIDORI ANZEN CO., LTD. (JP) 2014-10-02 US disclosed
EP-2774950-A1 RESIN COMPOSITION AND MOLDED BODY Midori Anzen Co., Ltd. (JP) 2014-09-10 EP disclosed
US-6762250-B2 TRANSPARENCY, FLUIDITY; CONTAINING POLYSILOXANE HAVING AT LEAST AROMATIC HYDROCARBON FUNCTIONALITY, CARBOXYLIC ACID ESTER AND/OR ETHER LINKAGES AND PHOSPHORIC ESTER GROUP ATTACHMENT MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-07-13 US disclosed
US-20040054116-A1 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION 2004-03-18 US disclosed